Sumatriptan (oral route of administration) for acute migraine attacks in adults
نویسندگان
چکیده
منابع مشابه
[Sumatriptan plus naproxen for acute migraine attacks in adults].
It is of great importance to improve acute treatment of migraine attacks. Non-steroidal anti-inflammatory drugs (NSAID) and triptans have different anti-nociceptive effects, so a combination of these could theoretically lead to more effective acute migraine treatment. A recent meta-analysis investigated the combined effect of sumatriptan and naproxen and found it to be more effective than sumat...
متن کاملComparison between Intravenous Sodium Valproate and Subcutaneous Sumatriptan for Treatment of Acute Migraine Attacks; Double-Blind Randomized Clinical Trial
Background: Sodium valproate (SV) has been approved for migraine prophylaxis and its intravenous form is used to treat acute migraine attacks. We compared the efficacy and safety of intravenous SV and subcutaneous Sumatriptan in managing acute migraine attacks. Methods: This double-blind randomized clinical trial divided 90 patients into two groups: one group received 400 mg of intravenous SV a...
متن کاملTreatment of acute migraine with subcutaneous sumatriptan.
Sumatriptan succinate, a 5-HT1D receptor agonist, constricts human cranial arteries. Two parallel-group trials for treatment of acute migraines were conducted in the United States. Adult patients were randomized and given either 6 mg of sumatriptan succinate subcutaneously (n = 734) or placebo (n = 370). At 1 hour, sumatriptan was significantly more effective than placebo in reducing moderate o...
متن کاملOral sumatriptan for the acute treatment of migraine in children and adolescents: yet another failed study.
Sumatriptan, a serotonin-1 receptor agonist specially developed for migraine, became available as a licensed product for adults more than 20 years ago. Since then, numerous controlled studies with sumatriptan have been carried out and it is widely used in adults. However, the story has not been as successful in children and adolescents as in adults. Of the few studies performed, most have shown...
متن کاملEfficacy and tolerability of oral sumatriptan in the treatment of acute migraine.
An open prospective study of the efficacy and tolerability of oral sumatriptan in the treatment of acute migraine attacks at the Kenyatta National Hospital, Nairobi, Kenya, is presented. Thirty two patients were initially recruited and 24 completed the trial giving a drop-out rate of 25%. The age range was 17 to 55 years with a mean of 35 years. Sumatriptan was found to be effective in 22 (92%)...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2012
ISSN: 1465-1858
DOI: 10.1002/14651858.cd008615.pub2